Research

Embedded Machine Intelligence Lab

Reprinted with permission from Biochemia Medica. The journal of Croatian Society of Medical Biochemistry and Laboratory Medicine. Biochemia Medica 2016;26(3):318-36  Blood...

A method and system for closed-loop, automated, closed, autotransfusion having a computer in electronic communication with a bedside monitor, an infusion pump, wherein the infusion pump is controlled by the computer, a blood collection canister for receiving shed mediastinal blood from a patient, means for filtering the blood, means for transferring the blood from the canister to the infusion pump and then into the patient, means for automatically taking a set of time-spaced measurements of a hemodynamic variable of the patient wherein the hemodynamic variable is coded into a multiplicity of digitally coded signals that are transmitted to the computer, and programming means for analysis of the digitally coded signals to determine the rate of the infusion pump, wherein the blood is infused at a high rate intermittently.

Abstract. Data collected in vivo is essential for advising decisions on drug screening and development and basic research, and animal models are used exten

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In the fingertip blood automatic sampling process, when the blood sampling point in the fingertip venous area, it will greatly increase the amount of bleeding without being squeezed. In order to accurately locate the blood sampling point in the ...

AbstractBackground. Demand continues to grow for patient-centric sampling solutions that enable collection of small volumes of blood outside of healthcare

Blood collection is a fundamental process in medical diagnostics, research, and treatment. The effectiveness and accuracy of diagnostic tests often depend on the quality of the blood sample collected. At BioTouch Global, we understand the critical

The introduction of the vacuum tube in 1949 revolutionized blood collection, significantly improving sample quality and patient comfort. Over the past 75 years, laboratory diagnostics have evolved drastically, from manual to automated processes, reducing required test volumes by over 1,000 times. Despite these advancements, venous blood collection presents logistical challenges, including centralized scheduling and a large volume of biological waste due to the imbalance between the needed blood volume (often very little) and the collected volume (often in excess). The COVID-19 pandemic further emphasized the need for decentralized healthcare solutions and patient empowerment. Capillary blood collection, widely used in point-of-care testing, offers a promising alternative, particularly for patients facing frequently, or difficulties with, venous sampling. The Leiden University Medical Center in the Netherlands experienced a 15 % reduction in volume of laboratory tests during and after the pandemic, attributed to patient preference for local blood collection and testing. To address these challenges, self-sampling devices are emerging, empowering patients and streamlining sample logistics. However, challenges such as cost, transportation regulations, and sample volume adequacy persists. Robust devices tailored for total lab automation and sustainable practices are crucial for widespread adoption. Despite hurdles, the integration of self-sampling into diagnostic processes is inevitable, heralding a shift towards patient-centered, proactive healthcare. Practical recommendations include robust device design, ease of use, affordability, sustainability, sufficient quality and acceptability by seamless integration into laboratory workflows. Although obstacles remain, self-sampling represents the future of laboratory diagnostics, offering convenience, cost-effectiveness, interoperability and patient empowerment.

In the fingertip blood automatic sampling process, when the blood sampling point in the fingertip venous area, it will greatly increase the amount of bleeding without being squeezed. In order to accurately locate the blood sampling point in the venous area, we propose a new finger vein image segmentation approach basing on Gabor transform and Gaussian mixed model (GMM). Firstly, Gabor filter parameter can be set adaptively according to the differential excitation of image and we use the local binary pattern (LBP) to fuse the same-scale and multi-orientation Gabor features of the image. Then, finger vein image segmentation is achieved by Gabor-GMM system and optimized by the max flow min cut method which is based on the relative entropy of the foreground and the background. Finally, the blood sampling point can be localized with corner detection. The experimental results show that the proposed approach has significant performance in segmenting finger vein images which the average accuracy of segmentation images reach 91.6%.

Circulating luteinizing hormone (LH) levels are an essential index of the functioning of the hypothalamic-pituitary control of reproduction. The role of numerous inputs and neuronal populations in the modulation of LH release is still unknown. ...

Updated European Association of Urology guidelines on sexual and reproductive health are presented, addressing the diagnosis and treatment of the most prevalent conditions in men. Patients must be fully informed of all relevant diagnostic and therapeutic options and, together with their treating phy …

The COVID-19 pandemic, caused by the SARS-CoV-2, represents an unprecedented challenge for healthcare. COVID-19 features a state of hyperinflammation resulting in a “cytokine storm”, which leads to severe complications, such as the development of ...

Overall, research strongly supports the routine clinical investigation of psychological factors, partner-related factors, context, and life stressors. A biopsychosocial model to understand how these factors predispose to sexual dysfunction is recommended.

The novel severe acute respiratory syndrome coronavirus 2 caused the coronavirus 2019 (COVID-19) pandemic that resulted in more than 150 million infections and 3.5 million deaths globally. COVID-19 affected men more than women, emerging with more ...

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These findings support the role played by cognitive and emotional factors on the predisposition and maintenance of male erectile dysfunction and suggest important implications for assessment and treatment of ED.

The novel severe acute respiratory syndrome coronavirus 2 caused the coronavirus 2019 (COVID-19) pandemic that resulted in more than 150 million infections and 3.5 million deaths globally. COVID-19 affected men more than women, emerging with more ...

A Proposed Framework and Timeline of the Spectrum of Disease Due to SARS-CoV-2 Infection: Illness Beyond Acute Infection and Public Health Implications

The psychological and sexual health of different populations are negatively affected during the coronavirus disease 2019 (COVID-19) pandemic. However, little is known about psychological distress and erectile function of male recovered patients with ...

Male sexual dysfunctions (MSDs) often remain undiagnosed and untreated in Asia compared to Europe due to conservative cultural and religious beliefs, socioeconomic conditions, and lack of awareness. There is a tendency for the use of traditional ...